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There is good scientific evidence about cannabinoids, and, in particular, cannabidiol (CBD), since it can offer control of the immune system and in turn provide protection against viral infections. Cannabidiol has already recognize for inhibiting fungi and bacteria. It´s like a new class of antibiotics due to the different mechanism of action of other antimicrobial agents.
Ebola´s a viral organism complex DNA that makes the cell engulf by pinocytosis. Then the virus hijacks the cell to replicate itself. This replication can involve many mutations in the DNA that make it difficult or impossible to create an effective vaccine. There are US patents that show evidence that cannabinoids have significant antiviral activity.
Normally, cells infected by the virus produce surface proteins that are foreign. The immune system attacks these cells when the surface protein´s identified as foreign. Ebola virus infection causes the cell to produce proteins that hide the virus from the immune system. The viral proteins are “hidden” from view (sterically protected), which hinders the cellular (therefore viral) destruction by the immune system. This mechanism allows the DNA virus to hide the infected cell by shielding it from the immune system.
The cause of death by this virus is the body´s own immune response to viral infection. This is what makes the mortality and morbidity of this infection so high. Subsequently. The virus activates immune killer cells to release the enzymes (cytokines) they possess. This release of enzymes causes other lymphocytes that release even more cytokines in a storm of release. This is a “cytokine storm.”
It causes small blood clots in all the arterioles, called; DIC or disseminated intravascular coagulation.
Causes massive coagulopathy where the blood doesn´t coagulate and simultaneously with the DICE (bleeding and coagulation occurs together). Toxic Shock Syndrome occurs when the release of cytokines causes the blood vessels. They expand to such a degree that there is a state of shock.
How CBD can help?
CBD has shown to reduce and prevent Toxic Shock and DICE.
Ebola virus also attacks adhesions between cells caused by killer cells immune to the release of VEGF (Vascular Endothelial Growth). Which results in the destruction of the tight junction between the cells. It causes a leakage of fluid between the cells until bleeding occurs. The inhibition of VEGF by CBD prevents the cellular junctions of haemorrhage.
Cannabinoids cause the inhibition of VEGF and the growth of Glioma brain tumors by this mechanism. It´s reasonable to predict that the inhibition of VEGF and other cytokines by cannabinoids during an Ebola infection. It will help the survival of this deadly disease. The stop of cytokine release will be a key feature of the treatment of this deadly disease.
The discovery and application of the endocannabinoid signalling system´s proving to be the control of virtually all diseases of humankind.
Cannabinoids are becoming a new class of drugs to treat infections of bacteria, fungi and viruses by different mechanisms of action.
Cannabinoids are becoming a new class of drugs to treat infections of bacteria, fungi and viruses by different mechanisms of action. That aren´t found in any other class of medicines. Cannabinoids are proving to have significant activity on many viruses. Including the Hepatitis C and the HIV virus to regulate by decreasing the immune response to infection.
To antiretroviral, cannabinoids are also anti-inflammatory. Which would also decrease the severity of the effects of cytokine storm, avoiding hemorrhagic complications.
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