How CBD can help for Migraines

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Let’s look at how CBD can help for Migraines.

Migraines are as mild to severe headaches. That are as a throbbing sensation that usually occurs on one side of the head. In addition to causing irritating and sometimes unbearable pain, migraine headaches can also trigger other symptoms such as vomiting, nausea, and sensitivity to light and sound.

migraine headaches can also trigger other symptoms such as vomiting, nausea, and sensitivity to light and sound

There are numerous forms of migraines, each with different characteristics. 70 to 90% of people experience migraine without aura, a type that lasts between 4 and 72 hours. And presents pulsating pain on one side of the head. Migraine with aura is another common form that derives from the neurological symptoms caused by the headache. Symptoms include blind spots in the field of vision, colored dots, tunnel vision and blinking lights in the eyes. Another form of migraine is chronic migraine, a type that can persist for more than 15 days in a month.

 there is no clear answer in the scientific literature so far, there are some indications that CBD can help for migraines

Research within this area is certainly very early and incomplete, in part due to the restrictions imposed on this molecule until recently. Although there is no clear answer in the scientific literature so far, there are some indications that CBD can help for migraines.  likewise

It´s thought that many of the effects of this molecule derived from its interaction with the endocannabinoid system. This system is composed of receptor sites that occur in many different cell types within the body. Also, works to regulate many physiological systems. These receptor sites known as CB1 and CB2 receptors. Chemicals synthesized in the body, known as endocannabinoids, regulate this system. These chemicals are similar in structure to the phytocannabinoids; the cannabinoids form the cannabis plant. Therefore, they have similar effects on the body.

The Endocannabinoid System

The endocannabinoid system has proposed as a great player in regards to migraine and its activation through the administration of CBD. An article published in the journal Experimental Neurology states. That this system can be involved centrally and peripherally in the processing of pain signals. In addition, this may be due in part to endocannabinoids inhibiting the release of neurotransmitters. That control pain signalling through the interaction of the CB1 receptor. The authors of the article claim that the endocannabinoid system could serve as a promising therapeutic tool to reduce the physiological and inflammatory elements of pain involved in migraines.

endocannabinoid system could serve as a promising therapeutic tool to reduce the physiological and inflammatory elements of pain involved in migraines

If this concept is true, then the lack of endocannabinoids within the system may contribute to migraine and other conditions. This condition, which now known as clinical endocannabinoid deficiency, could be the cause of migraines in some people.

Anandamide, or AEA, is one of several endocannabinoids synthesized in the human body. An article published in the journal Neuroendocrinology Letters states that this molecule has the ability to increase. Also, decrease the activity of certain serotonin receptors, which suggests that it has therapeutic applications within the domain of migraines. The authors of the article also affirm that the AEA is tonic active in the periaqueductal gray matter, a generator of migraine.hence

Other research published in the Journal of Headache and Pain has explored the role of administration of ALE with animal models. This research confirms that a dysfunction within the endocannabinoid system can contribute to the development of migraine attacks. The authors of the article also suggest that the modulation of the receptors of the endocannabinoid system, such as that which occurs with the administration of AEA, may be useful in the treatment of migraine pain.

In conclusion

The potential power of CBD oil in the treatment of migraine may lie in how it can manipulate the levels of ALE within the body, the endogenous cannabinoid that has found to relieve migraine attacks in some models. It has shown that CBD inhibits the uptake of AEA and the enzymes that degrade this molecule. This means that CBD allows anandamide to remain outside the cell for longer periods, where it can exert its aforementioned effects.

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