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Let´s look at Cannabinoids and Spasticity. Spasticity is a motor disorder characterized by involuntary muscle spasms that are usually caused by alterations in the brain and spinal cord. People who develop this disorder are affected by the involuntary and sometimes permanent contraction of the muscles. This contraction generates stiffness and shortening of the muscles and interferes with movements and functions such as swallowing, speech and balance. Patients experience a combination of paralysis. Increased activity of the tendon reflex and hypertonia. Usually described as a certain “tension” or “pull” in the muscles.
This disorder can occur in several symptom-related motor systems, as well as in metabolic disorders, such as multiple sclerosis, cerebral palsy, adrenoleukodystrophy, hypoxia, stroke and phenylketonuria. Also, spasticity can occur as an increase in muscle tone, cramps, contractions of movement, hyperreflexia of the tendon, abnormal posture, etc.
In recent years
Positive results had obtained in clinical trials that demonstrate the effectiveness of cannabinoids in treating spasticity. In addition, cannabinoids are being widely accepting by the medical community. And specialists recommend its use for the treatment of this motor disorder. Among the most important trials, the Spanish Society of Neurology carried out an observational study that included 50 patients treated with THC / CBD inhalation. In addition, it observed that this treatment was effective in 80% of patients. Who received instructions to inhale 5 times a day. With this information, the Spanish Society of Neurology concluded that. “THC / CBD seems to be a good alternative to the standard treatment of refractory spasticity.”
Another trial conducted by the Department of Neurology at the San Carlos Clinical Hospital in Madrid concluded that. “An administration through the oral mucosa of THC + CBD (1: 1) had approved in several EU countries, including Spain. In conclusion, clinical trials have shown a clear reduction in symptoms related to spasticity (rigidity, pain, sleep disturbance) in patients resistant to other treatments .”
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